Mechanism Of Action Of Metoprolol

• Blocks beta-adrenergic stimulation, beta receptors stimulate the heart and increase its rate, force of contraction & conductivity
• Beta-blocker protects the heart from too much activity. This medicine works by affecting the body’s response to some nerve impulses, especially in the heart.
• As a result, it slows down the heart rate and makes the heart more efficient at pumping blood around the body.

Therapeutic Indications Of Carelio 100 Mg Tablets

• Hypertension: High blood pressure is a common condition in which the long-term force of the blood against your artery walls is high enough that it may eventually cause health problems, such as heart disease.
• Angina pectoris.
• Cardiac arrhythmias, especially including supraventricular tachycardia, reduction of ventricular rate in atrial fibrillation, and in ventricular extrasystoles.
• Functional heart disorders with palpitations.
• Prevention of cardiac death and reinfarction after the acute phase of myocardial infarction.
• Prophylaxis of migraine.
• Stable chronic symptomatic heart failure with impaired systolic left ventricular function. Heart failure occurs when the heart muscle is weak and unable to pump enough blood to supply the body’s needs.

Method Of Administration Of Carelio 100 Mg Tablets

• Tablets should not be chewed or crushed.
• They should be swallowed together with at least half a glass of liquid.
• Concomitant intake of food does not influence bioavailability.
• Dosage should be adjusted individually to avoid bradycardia. The following is valid as guidelines:
• Hypertension: 47.5-95 mg metoprolol succinate (50-100 mg metoprolol tartrate) once daily.
• Angina pectoris: 95-190 mg metoprolol succinate (100-200 mg metoprolol tartrate) once daily. If necessary, the dose can be combined with nitrates.
• Cardiac arrhythmias: 95-190 mg metoprolol succinate (100-200 mg metoprolol tartrate) once daily.
• Functional heart disorders with palpitations: 95 mg metoprolol succinate (100 mg metoprolol tartrate) once daily. If needed, the dose may be increased to 190 mg metoprolol succinate (200 mg metoprolol tartrate) once daily.
• Preventive treatment after myocardial infarction: As maintenance dosage, 190 mg metoprolol succinate (200 mg metoprolol tartrate) is given once daily.
• Prophylaxis of migraine: 95-190 mg metoprolol succinate (100-200 mg metoprolol tartrate) once daily
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Carelio 100 Mg Tablets

• Dizziness or lightheadedness.
• Tiredness.
• Depression.
• Nausea.
• Dry mouth.
• Stomach pain.
• Vomiting.
• Gas or bloating.

Pregnancy & Breastfeeding Precautions While Taking Carelio 100 Mg Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Non-Pharmacological Treatments & Advice To Reduce Blood Pressure

• To measure blood pressure correctly:

1. Don’t eat or drink anything 30 minutes before you take your blood pressure.
2. Empty your bladder before your reading.
3. Sit in a comfortable chair with your back supported for at least 5 minutes before your reading.
4. Put both feet flat on the ground and keep your legs uncrossed.
5. Rest your arm with the cuff on a table at chest height.
6. Make sure the blood pressure cuff is snug but not too tight. The cuff should be against your bare skin, not over clothing.
7. Do not talk while your blood pressure is being measured.

• You will also find the following Non-Pharmacological treatments effective in blood pressure reduction:

1. Lose extra pounds and watch your waistline
2. Exercise regularly
3. Eat a healthy diet
4. Reduce sodium in your diet
5. Quit smoking
6. Cut back on caffeine
7. Reduce your stress
8. Monitor your blood pressure at home and see your doctor regularly

Warnings & Special Precautions While Taking Carelio 100 Mg Tablets

• Metoprolol may aggravate the symptoms of peripheral arterial circulatory disorders
• In bronchial asthma or other chronic obstructive lung diseases, adequate broncho-dilating therapy should be given concomitantly. The dose of beta2-stimulants may need to be increased.
• Treatment with beta-blockers may aggravate the treatment of an anaphylactic reaction
• Tell your doctor or pharmacist about all medications you take even those taken without prescription

Storage Conditions Of Carelio 100 Mg Tablets

• Store below 25°c
• Don’t refrigerate
• Keep this medicine out of the sight and reach of children.
• Store in the original package to protect from moisture.
• Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

Normal Ranges

• Normal: Blood pressure numbers of less than 120/80 mm Hg
• Elevated: is when readings consistently range from 120-129 systolic and less than 80 mm Hg diastolic.
• Hypertension Stage 1: is when blood pressure consistently ranges from 130-139 systolic or 80-89 mm Hg diastolic.
• Hypertension Stage 2: is when blood pressure consistently ranges at 140/90 mm Hg or higher.
• Hypertensive crisis: This stage of high blood pressure requires medical attention. If your blood pressure readings suddenly exceed 180/120 mm Hg, wait five minutes and then test your blood pressure again. If your readings are still unusually high, contact your doctor immediately. You could be experiencing a hypertensive crisis.